TABLE 34-1
Circulating Levels and Origin of Sex Steroids
Adult Men
Adult Women
Approximate Contribution (%) of
Approximate Contribution (%) of
Plasma Level
-----------------------------------------------
Cycle
Plasma Level
--------------------------------------------
Steroid
(ng/dL)
Testes
Adrenal
Periphery
Phase*
(ng/dL)
Ovary
Adrenal
Periphery
Testosterone (T)
700
90
5
5 (A, DHEA)
—
40
60
1 0
30 (A, DHEA)
Dihydrotestosterone
40
2 0
—
80 (T, A)
—
2 0
—
—
100 (A, T)
(DHT)
Androstenedione (A)
115
60
30
10 (DHEA, T)
_
160
60
30
10 (DHEA)
Dehydroepiandro-
640
1 0
85
5 (DHEAS)
—
500
1 0
85
5 (DHEAS)
sterone (DHEA)
DHEA sulfate (DHEAS)
260,000
_
1 0 0
_
_
130,000
_
1 0 0
_
Estradiol (E2)
3
30
—
70 (T, A)
EF
10 1
LF
50 f
95
—
5 (A, DHEA, Ej)
ML
2 0
J
Progesterone (P)
30
70
30
—
F
1 0 0
70
30
—
L
1 1 0 0
95
5
—
*EF = Early follicular phase; LF = late follicular phase; ML= midluteal phase; F = follicular phase; L = luteal phase.
